Center Graduate hosts NIH Director

 Dr. Saied A. Jaradat (right), who received his PhD in the Center in 1998 and is now Director of the Princess Haya Biotechnology Center and Assistant Professor of Molecular and Human Genetics at the Jordan University of Science and Technology, is shown hosting Dr. Elias A. Zerhouni (left), Director of the National Institutes of Health, during a visit on June 17.

Graduate Student Awards

Center graduate students have done well in national competitions recently. MD/PhD student, Lesley Lawrenson received a three year Predoctoral Traineeship Award through the Department of Defense for her project “Genomic Instability as a Driving Force for Breast Cancer.” Ms. Lawrenson is a member of Dr. Wayne Lancaster’s lab. MD/Ph.D student Daniel Barkmeier received a predoctoral fellowship from the Epilepsy Foundation of America for his research in animal models that simulate epileptic events. Mr. Barkmeier is a member of Dr. Jeffrey Loeb’s lab. More.. Dr. Loeb’s separate receipt of a grant from the National Institutes of Health to study abnormal epileptic brain activities present in patients with recurrent seizures was announced by local media. Dr. Loeb is the Associate Director of the Center and Associate Professor of Neurology and of Molecular Medicine and Genetics. More..

New Faculty Member

The Center is pleased to announce that Dr. Kezhong Zhang has joined our faculty as Assistant Professor of Molecular Medicine and Genetics and of Immunology and Microbiology. Dr. Zhang was previously a Research Investigator in the Department of Biological Chemistry of the University of Michigan Medical School, where his research focus was intracellular stress signaling in inflammation and lymphopoiesis, roles of the unfolded protein response, and the role of cellular stress and immunological mechanisms in cardiovascular disease. Dr. Zhang was recently awarded an AHA Independent Scientist Development Grant for his research in “Mechanisms and Roles of Intracellular Stress-induced Inflammatory Response in Atherosclerosis.” His Center office is in Scott Hall, Room 3202.

 Dr. Helena Kuivaniemi, Professor of Molecular Medicine and Genetics and of Surgery, and Dr. Gerard Tromp, Associate Professor of Molecular Medicine and Genetics and of Neurology, along with their research groups, have been involved in an international collaborative study on genetic risk factors for various vascular diseases. This multi-center study with 68 investigators from 28 sites has been accepted for publication in Nature Genetics. More...
 

CMMG Newsletter, Summer 2007

News Archive

Recent Publications of Center faculty:

Kunarso G, Wong KY, Stanton LW, and Lipovich L. Detailed characterization of the mouse embryonic stem cell transcriptome reveals novel genes and intergenic splicing associated with pluripotency. BMC Genomics 9(1):155 (e-publication), 2008 more...

Monaghan KG, Feldman GL, Palomaki GE, Spector EB; Ashkenazi Jewish Reproductive Screening Working Group; Molecular Subcommittee of the ACMG Laboratory Quality Assurance Committee. Technical standards and guidelines for reproductive screening in the Ashkenazi Jewish population. Genet Med. 2008 Jan;10(1):57-72. more...

Uddin M, Goodman M, Erez O, Romero R, Liu G, Islam M, Opazo JC, Sherwood CC, Grossman LI, Wildman DE. Distinct genomic signatures of adaptation in pre- and postnatal environments during human evolution. Proc Natl Acad Sci U S A. 2008 Mar 4;105(9):3215-20. Epub 2008 Feb 27. more...

Ballard PL, Truog WE, Merrill JD, Gow A, Posencheg M, Golombek SG, Parton LA, Luan X, Cnaan A, Ballard RA. Plasma biomarkers of oxidative stress: relationship to lung disease and inhaled nitric oxide therapy in premature infants. Pediatrics. 2008 Mar;121(3):555-61. more...

Uddin M, Opazo JC, Wildman DE, Sherwood CC, Hof PR, Goodman M, Grossman LI. Molecular evolution of the cytochrome c oxidase subunit 5A gene in primates. BMC Evol Biol. 2008 Jan 15;8:8. more...

Grandis M, Vigo T, Passalacqua M, Jain M, Scazzola S, La Padula V, Brucal M, Benvenuto F, Nobbio L, Cadoni A, Mancardi GL, Kamholz J, Shy ME, Schenone A.
Different Cellular and Molecular Mechanisms for Early and Late-onset Myelin Protein Zero Mutations. Hum Mol Genet. 2008 Mar 12 [Epub ahead of print]. more...

Chandran NS, Vunnava P, Wu Y, Kapatos G. Specificity proteins Sp1 and Sp3 interact with the rat GTP cyclohydrolase I proximal promoter to regulate transcription. J Neurochem. 2008 Mar;104(5):1233-48. Epub 2007 Nov 13. more...

Kuivaniemi H, Platsoucas CD, Tilson MD 3rd. Aortic aneurysms: an immune disease with a strong genetic component. Circulation. 2008 Jan 15;117(2):242-52. more...

Weiss JS, Kruth HS, Kuivaniemi H, Tromp G, Karkera J, Mahurkar S, Lisch W, Dupps WJ Jr, White PS, Winters RS, Kim C, Rapuano CJ, Sutphin J, Reidy J, Hu FR, Lu da W, Ebenezer N, Nickerson ML. Genetic analysis of 14 families with Schnyder crystalline corneal dystrophy reveals clues to UBIAD1 protein function. Am J Med Genet A. 2008 Feb 1;146(3):271-83. more...

Grandis M, Vigo T, Passalacqua M, Jain M, Scazzola S, La Padula V, Brucal M, Benvenuto F, Nobbio L, Cadoni A, Mancardi GL, Kamholz J, Shy ME, Schenone A. Different Cellular and Molecular Mechanisms for Early and Late-onset Myelin Protein Zero Mutations. Hum Mol Genet. 2008 Mar 12 [Epub ahead of print]. more...

Padua L, Shy ME, Aprile I, Cavallaro T, Pareyson D, Quattrone A, Rizzuto N, Vita G, Tonali P, Schenone.
A Correlation between clinical/neurophysiological findings and quality of life in Charcot-Marie-Tooth type 1A. J Peripher Nerv Syst. 2008 Mar;13(1): 64-70. more...

Chatterjee M, Tainsky MA. Non-traditional immun- ogens and their application to immunotherapy. Curr Opin Mol Ther. 2008 Feb;10(1):62-7. more...

Liang J, Wang J, Azfer A, Song W, Tromp G, Kolat- tukudy PE, Fu M. A Novel CCCH-Zinc Finger Protein Family Regulates Proinflammatory Activation of Macro- phages. J Biol Chem. 2008 Mar 7;283 (10): 6337 -46. Epub 2008 Jan 4. more...

Wang H, Sammel MD, Tromp G, Gotsch F, Halder I, Shriver MD, Romero R, Strauss JF 3rd. A 12-bp deletion in the 5'-flanking region of the SERPINH1 gene affects promoter activity and protects against preterm premature rupture of membranes in African Americans. Hum Mutat. 2008 Feb;29(2):332. more...