abnormalities; suspected inherited disorders; mental
retardation and metabolic disorders.
neurobiology; Huntington’s disease; neuron-specific
gene expression; demyelinating disease.
Biolistic augmentation of wound healing.
Use of molecular technologies in the diagnosis of
genetic diseases; clinical genetics and dysmorphology;
educational programs in medical genetics residency
L. Finley, Jr.
Regulatory networks that control cell proliferation;
cell cycle regulation during development; yeast
Neurogenetics; molecular biology of meiotic disorders;
molecular pathogenesis of glial tumors; homeobox genes.
N. Giroux, Functional
genomics of gene-environment interactions; genetic
toxicology and pharmacogenetics; genome stability and
meiotic differentiation; cellular biosensors and
evolution, with emphasis on globin genes and the
X-linked HPRT gene.
Molecular pathogenesis of CNS diseases; molecular
characterization of the claudin family of integral
membrane tight junction proteins during development in
brain, testes and inner ear using transgenic and
homologous recombination in embryonic stem cells.
E. Greb, Educational
programs in human genetics and genetics counseling.
I. Grossman, Molecular
genetics and evolution of the electron transport chain;
cytochrome c oxidase; mitochondria and
biology of insulin action; insulin receptor regulation
in insulin resistance.
H.Q. Heng, Chromosome
and chromatin structure; FISH mapping; genetic control
Kamholz, Regulation of
myelination; molecular pathophysiology of demyelinating
Cellular and molecular biology of monoamine
neurotransmitter secreting neurons.
A. Krawetz, Gene
therapy; control of development and differentiation;
expression of connective tissue genes and genes
controlling spermatogenesis; computer-assisted sequence
Molecular biology and genetics of aortic aneurysms.
Extracellular matrix; metalloproteinases; gene
regulation; development; disease.
Pappillomaviruses: molecular biology, evolution, and
role in human carcinogenesis; cancer cell genome
Regulation of smooth muscle gene expression during
neuroscience; molecular mechanisms in synapse formation;
neuregulins and neurotrophins in synaptic development;
functional genomic study of the pathogenesis of
Human/mammalian genetics and cytogenetics; chromosome
structure and function; genome organization.
Study of gene expression during differentiation; gene
transcription; hormone action.
E. Shy, Molecular
biology of Schwann cell axonal interactions; gene
therapy in the peripheral nervous system.
cancer and genomic instability; control of transcription
in cancer cells; Li-Fraumeni familial cancer syndrome.
transmission in meiosis and mitosis; structural and
regulatory components of centromeres in higher
epidemiology and linkage analysis; molecular biology and
genetics of intracranial aneurysms; the Blau syndrome;
bioinformatics and genomics.
Bioinformatics, Control of DNA replication and
segregation; regulation of the cell division cycle.