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Center for Molecular Medicine and Genetics.
"The Human Genome Project is producing the rosetta stone of biological information
that will allow the ultimate translation of the genetic story," he says.
"Still, it will require the next century of study to truly understand this message
and how the thousands of genes function in concert to produce the normal story of life, or
how they malfunction to cause diseases such as cancer and birth defects. What is
clear already is that the genes of a fruit fly, a mouse, and a human are incredibly
similar and that knowledge about one of these systems enhances greatly our understanding
about the other two.
"Wayne State University is already strong in many areas of developmental biology, and
we want to enhance our position by building an across-the-campus program that focuses onto
this common theme the attention of scientists at the laboratory bench and clinicians at
the bedside," says Hughes. |
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To this end, Wayne State already has excellent fruit fly
developmental geneticists as well as mouse and human geneticists. Now it is in the
process of recruiting several new faculty members, including four vertebrate developmental
biologists with expertise in mammalian mouse systems. Wayne State is also planning a
new high quality transgenic facility, which will make mouse models of human disease.
The Developmental Biology Program plans to focus initially on three main areas: the
development of the nervous system; cancer genetics; and the understanding of
developmentally important pathways, which help explain how genes interact to give each
of us a unique set of features as humans and individuals.
For more information about the Developmental Biology Program, please visit
the World Wide Web at URL:
http://sun2.science.
wayne.edu/~devbio |
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tists and clinician-investigators are uncovering the mysteries of the mammalian
genome and evolving their findings into translational research and technology
transfer. Every day they are pushing the boundaries of knowledge.
As the number of people affiliated with the Center has grown, it has become increasingly
important to find ways to communicate with each other and build a sense of cohesion.
We already have some methods in place--from regular meetings to informal gatherings.
In the months ahead, we will be looking at other ways as well and welcome your input into
this process. |
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In the meantime, this publication continues to be an important tool for providing
valuable news and information about the Center's people, research, programs and
activities. In addition to a new look for the newsletter, we have added some new
columns that we hope you will find useful. On page 7, for example, you will find a
new section for faculty, student and alumni news. We hope you will let us know of
any important accomplishments and recognitions for future issues.
This issue of Advances features a wide range of activities and efforts at the
Center. On page 3, you'll meet Mark Hughes, M.D., Ph.D., and learn how his
revolutionary research in single cell biology and early human development |
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is helping families around the world. On page 1, you'll read about the Center's
involvement in the creation of a comprehensive developmental biology program at Wayne
State University, Karmanos Cancer Institute, and Detroit Medical Center. On page 5,
you'll get an interesting overview of the Human Genome Project. On page 4, you'll
discover how the Center's new Biotechnology/Technology Transfer Program can help increase
your grant approval success rate.
I am excited about the positive momentum of change and development at the Center and
welcome your continued input and involvement as we move forward. I look forward to
your feedback and comments about Advances. |
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