SALIENT
PUBLICATIONS:
1.
Gow A,
Friedrich Jr VL, Lazzarini RA (1992) Myelin basic protein gene contains
separate
enhancers for
oligodendrocyte
and Schwann cell expression.
J. Cell Biol.
119,
605-616.
2. Gow A,
Friedrich Jr VL, Lazzarini RA (1994) intracellular transport and
sorting
of the
oligodendrocyte
transmembrane
proteolipid protein.
J. Neurosci. Res.
37, 563-573.
3. Gow A,
Friedrich Jr VL, Lazzarini RA (1994) Many naturally occurring mutations
of myelin
LP impair its
intracellular
transport.
J. Neurosci. Res.
37, 574-583.
4. Gow A,
Lazzarini RA (1996) A cellular mechanism governing the severity of
Pelizaeus-
Merzbacher disease.
Nat. Genet. 13,
422-428.
5.
Gow
A, Gragerov A, Gard A, Colman DR, Lazzarini RA (1997)
Conservation
of topology,
but not conformation,
of the proteolipid proteins of the myelin sheath.
J. Neurosci. 17,
181-189.
6.
Gow
A (1997) Redefining the lipophilin family of proteolipid
proteins.
J. Neurosci. Res.
50,
659-664.
7.
Gow
A, Southwood CM, Lazzarini RA (1998) Disrupted proteolipid
protein
trafficking
results in
oligodendrocyte
apoptosis in animal models of Pelizaeus-Merzbacher disease.
J. Cell Biol.
140,
925-934.
8.
Gow
A, Southwood CM, Li JS, Pariali M, Bronstein JM, Riordan G,
Kachar B, Lazzarini
RA (1999) CNS Myelin And
Sertoli Cell Tight Junction Strands Are Absent In
Osp/Claudin 11-Null Mice.
Cell 99,649-659.
9.
Stecca B, Southwood CM, Gragerov A, Kelley KA, Friedrich VL, Gow
A (2000) The
evolution of lipophilin
genes from invertebrates to tetrapods: DM-20 cannot replace
proteolipid protein in
CNS myelin.
J. Neurosci. 20,
4002-4010.
10.
Southwood CM, Gow A (2001)
Insights
into the mechanisms of oligodendrocyte
apoptosis from
hypomyelinated
mice.
Micros. Res. Tech.
52, 700-708.
11. Southwood CM, Gow
A (2001) Functions of OSP/claudin 11-containing parallel
tight
junctions: implications
from the knockout mouse.
in Tight Junctions.
(Anderson JM and Cereijido M, eds) 2nd ed. CRC Press.
12.
Southwood CM, Garbern J, Jiang W, Gow A
(2002) The unfolded
protein response
modulates disease severity in
Pelizaeus-Merzbacher Disease. Neuron, 36, 585-596.
13.
Gow A
(2002) The COS-7
cell in vitro paradigm to study myelin proteolipid protein 1
gene mutations. in: Methods in Molecular
Medicine, (Potter T, ed), Humana Press,
Totowa and New Jersey, pp. 263-275.
14. Gow A,
Sharma R (2003) The
unfolded protein response in protein aggregating diseases.
Neuromolec. Med., 4, 73-94.
15. Shy M, Hobson G, Boespflug-Tanguy O, Garbern J, Sperle K,
Jain M, Li W, Gow
A,
Rodriguez D, Bertini E, Mancias P,
Krajewski K, Lewis RA, Kamholz J, members
of the ENBDD (2003) Schwann cell
expression of PLP1 but not its alternatively spliced
isoform DM20 is necessary to prevent
demyelinating peripheral neuropathy.
Ann. Neurol., 53, 354-365.
16. Yang LV, Heng HH, Southwood CM, Gow A, Li L
(2003) Alternate
promoters and
polyadenylation regulate tissue-specific
expression of Hemogen isoforms during
hematopoisis and spermatogenesis. Dev.
Dyn. 228, 606-616.
17. Gow A,
Davies C, Southwood
CM, Frolenkov G, Chrustowski M, Ng L, Yamauchi D,
Marcus DC, Kachar B (2004) Deafness in
Claudin 11-null mice reveals the critical
contribution of basal cell tight
junctions to stria vascularis function.
J Neurosci., 24(32), 7051-7062.
18. Gow
A (2004)
The Claudin 11 gene. In Myelin Biology and Disorders,
(Lazzarini, RA ed.), Vol. 1, Elsevier
Science, pp. 565-578.
19. Gow
A (2004)
Protein misfolding as a disease determinant. In Myelin Biology and
Disorders, (Lazzarini, RA ed.), Vol. 2,
Elsevier Science, pp 1009-1036.
20. Southwood
CM, Garbern J, Kamholz J, Arroyo E, Gow A
(2004) CNS Myelin
Paranodes
Require Nkx6-2 Homeoprotein
Transcriptional Activity for Normal Structure.
J. Neurosci., 24, 11215-11225.
21. Xin M, Wu F-F, Ma Z, Gow A, Lu
QR (2004) Regulation of Oligodendrocyte
Myelination by the Basic
Helix-Loop-Helix Transcription Factor Olig1 in the
Developing Brain. J. Neurosci., submitted.
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