SALIENT PUBLICATIONS:
1.   Gow A, Friedrich Jr VL, Lazzarini RA (1992) Myelin basic protein gene contains separate
      enhancers for oligodendrocyte and Schwann cell expression.
      J. Cell Biol. 119, 605-616.
2.   Gow A, Friedrich Jr VL, Lazzarini RA (1994) intracellular transport and sorting of the
      oligodendrocyte transmembrane proteolipid protein.
      J. Neurosci. Res. 37, 563-573.
3.   Gow A, Friedrich Jr VL, Lazzarini RA (1994) Many naturally occurring mutations of myelin
      LP impair its intracellular transport.
      J. Neurosci. Res. 37, 574-583.
4.   Gow A, Lazzarini RA (1996) A cellular mechanism governing the severity of Pelizaeus-
      Merzbacher disease.
      Nat. Genet. 13, 422-428.
5.   Gow A, Gragerov A, Gard A, Colman DR, Lazzarini RA (1997) Conservation of topology,
      but not conformation, of the proteolipid proteins of the myelin sheath.
      J. Neurosci. 17, 181-189.
6.   Gow A (1997) Redefining the lipophilin family of proteolipid proteins.
      J. Neurosci. Res. 50, 659-664.
7.   Gow A, Southwood CM, Lazzarini RA (1998) Disrupted proteolipid protein trafficking
      results in oligodendrocyte apoptosis in animal models of Pelizaeus-Merzbacher disease.
      J. Cell Biol. 140, 925-934.
8.   Gow A, Southwood CM, Li JS, Pariali M, Bronstein JM, Riordan G, Kachar B, Lazzarini
      RA (1999) CNS Myelin And Sertoli Cell Tight Junction Strands Are Absent In
      Osp/Claudin 11-Null Mice.
      Cell 99,649-659.
9.   Stecca B, Southwood CM, Gragerov A, Kelley KA, Friedrich VL, Gow A (2000) The
      evolution of lipophilin genes from invertebrates to tetrapods: DM-20 cannot replace
      proteolipid protein in CNS myelin.
      J. Neurosci. 20, 4002-4010.
10.  Southwood CM, Gow A (2001) Insights into the mechanisms of oligodendrocyte
      apoptosis from hypomyelinated mice.
      Micros. Res. Tech. 52, 700-708.
11. Southwood CM, Gow A (2001) Functions of OSP/claudin 11-containing parallel tight
      junctions: implications from the knockout mouse.
      in Tight Junctions. (Anderson JM and Cereijido M, eds) 2nd ed. CRC Press.
12. Southwood CM, Garbern J, Jiang W, Gow A (2002) The unfolded protein response
      modulates disease severity in Pelizaeus-Merzbacher Disease. Neuron, 36, 585-596.
13. Gow A (2002) The COS-7 cell in vitro paradigm to study myelin proteolipid protein 1
      gene mutations. in: Methods in Molecular Medicine, (Potter T, ed), Humana Press,
      Totowa and New Jersey, pp. 263-275.
14Gow A, Sharma R (2003) The unfolded protein response in protein aggregating diseases.
      Neuromolec. Med., 4, 73-94.

15. Shy M, Hobson G, Boespflug-Tanguy O, Garbern J, Sperle K, Jain M, Li W, Gow A,
      Rodriguez D, Bertini E, Mancias P, Krajewski K, Lewis RA, Kamholz J, members
      of the ENBDD (2003) Schwann cell expression of PLP1 but not its alternatively spliced
      isoform DM20 is necessary to prevent demyelinating peripheral neuropathy.
      Ann. Neurol., 53, 354-365.
16. Yang LV, Heng HH, Southwood CM, Gow A, Li L (2003) Alternate promoters and
      polyadenylation regulate tissue-specific expression of Hemogen isoforms during
      hematopoisis and spermatogenesis. Dev. Dyn. 228, 606-616.
17Gow A, Davies C, Southwood CM, Frolenkov G, Chrustowski M, Ng L, Yamauchi D,
      Marcus DC, Kachar B (2004) Deafness in Claudin 11-null mice reveals the critical
      contribution of basal cell tight junctions to stria vascularis function.
      J Neurosci., 24(32), 7051-7062.
18.  Gow A (2004) The Claudin 11 gene. In Myelin Biology and Disorders,
      (Lazzarini, RA ed.), Vol. 1, Elsevier Science, pp. 565-578.
19.  Gow A (2004) Protein misfolding as a disease determinant. In Myelin Biology and
      Disorders, (Lazzarini, RA ed.), Vol. 2, Elsevier Science, pp 1009-1036.
20. Southwood CM, Garbern J, Kamholz J, Arroyo E, Gow A (2004) CNS Myelin Paranodes
      Require Nkx6-2 Homeoprotein Transcriptional Activity for Normal Structure.
      J. Neurosci., 24, 11215-11225.
21. Xin M, Wu F-F, Ma Z, Gow A, Lu QR (2004) Regulation of Oligodendrocyte
      Myelination by the Basic Helix-Loop-Helix Transcription Factor Olig1 in the
      Developing Brain. J. Neurosci., submitted.

 
 
 

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