DETROIT MEDICAL CENTER
| Cheryl Hess, MS, CGC.
Ms. Hess is a genetic counselor at DMC University Laboratories.
She currently serves as a client liasion to those ordering tests
performed within the Molecular Genetics Laboratory and provides
additional support to the in-house Cytogenetics and Biochemical
Genetics Laboratories. Ms. Hess is also involved in reviewing
genetic test requests from within the Detroit Medical Center, to ensure
accurate and appropriate utilization of specialized assays that
necessitate the use of an outside reference laboratory. Ms. Hess
received her Master of Science in Genetics from Case Western Reserve
University and is certified by the American Board of Genetic
Counseling. She is an adjunct assistant professor in Molecular Medicine
and Genetics at Wayne State University and enjoys providing both
academic and clinical education to students at varying levels of
medical training. Ms. Hess has previously worked as a clinical
counselor in both a reproductive, and general genetics setting.
She is interested in the styles and effectiveness of clinician-patient
communication, as well as clinicians' working knowledge of genomic
The Biochemical Genetics Laboratory
provides confirmatory testing for inborn errors of metabolism, along
with monitoring of the metabolic status of affected patients. Tests
range from gas chromatography/mass spectrometry analysis of complex
mixtures from urine (such as organic acids) to specific enzyme activity
determination. Analysis of amino acids is also provided. This
laboratory provides rapid turnaround time with an experienced staff.
Additional tests may be added as needed to provide service to
physicians and patients.
| Lidong Zhai, PhD
Dr. Zhai is a Biochemical Geneticist and is the Director of the
Biochemical Genetics Laboratory. Dr. Zhai is originally from China,
having trained and worked across the United States. His Ph.D. training
at the University of Alabama at Birmingham was pivotal in directing his
career. The overall experience catapulted him into a career directing
genetic testing in a variety of settings. He has directed testing of
newborns for state PKU programs, testing of pregnant women to assess
Down Syndrome and neural tube defect risks, and esoteric biochemical
tests to diagnose genetic defects of metabolism. His laboratory at The
Detroit Medical Center is a biochemical metabolic genetic testing
facility which supports two areas; the continued esoteric tests
provided by the DMC Core Lab and the expansion of the test menu, and
secondly, to support the diagnostic workup and monitoring of newborns
who test positive for a genetic disorder at the Michigan Newborn
Screening Laboratory in Lansing.
at DMCUL is one of the largest comprehensive university based
diagnostic laboratories in Michigan. Our lab specializes in chromosome
analysis, cancer cytogenetics, and molecular diagnosis by fluorescence
in situ hybridization (FISH). We serve over 4,000 patients each year
and take pride in providing accurate, efficient, high quality service
with short turnaround times.
||Anwar N. Mohamed, MD Dr.
Anwar Mohamed is board-certified by the American Board of Medical
Genetics in Clinical Cytogenetics. She is a Professor in the Department
of Pathology at Wayne State University, and the Director of the
Clinical Cytogenetics laboratory at Detroit Medical center. Dr Mohamed
received her M.D. degree from University of Mosul/Iraq, and a Master in
Genetics from Cornell University/New York. She completed her
post-doctoral training in cancer Genetics at Memorial Sloan-Kettering
Cancer Institute. She has over 25 years of
experience in clinical cytogenetic including chromosome analysis ,
FISH, and microarray. Her diagnostic experience is in leukemia,
lymphoma, and other hematological malignancies and solid tumors. Dr
Mohamed severed on the Cytogenetic working committee for South West
Oncology Group. She has authored or co-authored more than 90
publications in Cancer Cytogenetics. Dr Mohamed is also the program
Director of the ABMG clinical laboratory training program.
||Saleh A.P. Ebrahim, MD
Dr. Ebrahim is a clinical cytogeneticist with over 22 years of
experience in prenatal, postnatal, and cancer cytogenetics, fluorescent
in situ hybridization (FISH), and chromosomal microarray/array CGH. Dr.
Ebrahim is a diplomat of the American Board of Medical Genetics
(Clinical Cytogenetics) and has considerable experience in the
organization and management of high volume cytogenetics laboratory.
During his 22 years at the DMCUL cytogenetics laboratory and WSU as a
cytogenetics laboratory director, he has performed chromosome analysis,
FISH, and chromosomal microarray on several thousands of samples
including chorionic villi samples (CVS), amniotic fluid, placental
tissue, peripheral blood, bone marrow, as well as other tissue samples.
The DMCUL cytogenetics laboratory is one of the largest comprehensive
university based diagnostic laboratory in Michigan. The laboratory
continues its commitment to provide high quality and superior
laboratory services to DMC/WSU physicians and other healthcare
organizations in Michigan and beyond. Over the years, the cytogenetics
laboratory has remained on the cutting edge of its profession.
Diagnostic Laboratory provides DNA-based testing services for
diagnosis, carrier detection and prenatal diagnosis for over 20 genetic
disorders. Furthermore, genetic testing is also available for the
diagnosis of hematological malignancies and to monitor disease status.
Molecular techniques are used for direct mutation analysis, which
allows rapid and accurate testing of patient samples. Once a mutation
in a family is identified, genetic testing for other family members is
available, providing crucial information in the provision of genetic
counseling and determination of recurrence risk.
||Gerald Feldman, MD, PhD
Dr. Feldman is the Director of Clinical Genetics Services, Director of
the Medical Genetics Residency Program, and Director of the Molecular
Genetics Diagnostic Laboratory. He is an associate professor in the
CMMG and the Departments of Pathology and Pediatrics. Dr. Feldman
obtained his PhD and MD from the Medical College of Virginia. He did a
pediatric residency and postdoctoral fellowships in clinical genetics
and clinical biochemical/molecular genetics at Baylor College of
Medicine. He is board certified in pediatrics, clinical genetics and
clinical biochemical/molecular genetics. Dr. Feldman coordinates
patient care in all the genetics clinics of the Detroit Medical Center.
His research interests include the molecular diagnosis of cystic
fibrosis and the development of expanded newborn screening for genetic
conditions. He is currently President-Elect of the Association of
Professors of Human and Medical Genetics and Chair of the Medical
Genetics Residency Review Committee of the Accredidation Council for
Graduate Medical Education. He was recently elected to the Board of
Directors of the American College of Medical Genetics.
||Fatimah Nahhas, PhD FACMG Dr.
Nahhas is the technical director of the Molecular Genetics Diagnostic
Laboratory at Detroit Medical Center. She is an assistant professor at
the Department of Pathology DMC/WSU. She provides molecular genetics
expertise in the analysis and interpretation of a wide range of genetic
tests for conditions such as Huntington disease, Fragile X syndrome,
Cystic Fibrosis and malignant tumors. She supervises medical and
genetic counseling students as well and genetics and pathology
residents who rotate through the laboratory. Dr Nahhas did her graduate
and post doctorate training at WSU SOM.
||Erin Wakeling, PhD is
a technical director of the Molecular Genetics Diagnostic Laboratory at
the Detroit Medical Center. She did her graduate training in genetics
at Michigan State University and her post-doctoral clinical molecular
genetics training at WSU SOM. Dr. Wakeling is involved in developing
new assays and interpreting genetic test results for a wide range of
inherited diseases and cancers. She also supervises genetics residents
and genetic counseling students during their rotation through the
|Genetic Counseling Graduate Program
Center for Molecular Medicine and Genetics
Wayne State University School of Medicine
3127 Scott Hall
540 E. Canfield Avenue
Detroit, MI 48201
Fax: (313) 577-9137