| Faculty Member |
|
Research Focus |
Major Faculty Techniques |
| Rodrigo Andrade
313-577-6006
randrade@med.wayne.edu
|
 |
Electrophysiology and molecular biology of serotonergic and cholinergic synaptic transmission in the CNS;
Signaling by neuronal G protein coupled receptors;
Anatomy and physiology of the cerebral cortex. |
Brain slice electrophysiology and live cell imaging including patch clamp recordings, confocal microscopy, and acute genetic manipulations of neurons implemented using particle mediated gene transfer and in utero electroporation techniques;
Optogenetic manipulations of neuronal activity and neuronal signaling. |
|
| Michael Bannon
313-993-4271
mbannon@med.wayne.edu
|
 |
Molecular mechanisms controlling neural gene expression;
Molecular neuropathology of drug abuse and Parkinson’s disease. |
Analysis of human postmortem tissue using cellular/molecular techniques;
Functional genomics and associated bioinformatics;
Intracerebral viral injections in animal models. |
|
| Diane Chugani
313-993-3847
dchugani@pet.wayne.edu
|
|
Autism |
Pet and MRI imaging |
|
| Donald DeGracia
313-577-6745
ddegraci@med.wayne.edu
|
 |
Brain ischemic injury |
Whole animal physiology, histology and molecular biology |
|
| Aloke Dutta
313-577-1064
adutta@wayne.edu
|
|
CNS Drug Discovery and Characterization |
Medicinal Chemistry and Pharmacology |
|
| Alexander Gow
313-577-9401
agow@med.wayne.edu
Lab Information |
 |
Neurobiology of multiple sclerosis, Pelizaeus Merzbacher diseases and other CNS white matter diseases;
computational models of myelin; mechanisms of hearing loss;
neural processing in the auditory pathway; fate mapping of adult stem cells. |
Knockout and transgenic mice;
Cre-lox and genetic switches;
mouse models of human disease;
light and electron microscopy;
mouse behavior: motor co-ordination, auditory and visual pathways;
electrophysiology;
functional genomics. |
|
| Zhou-Hua Pan
313-577-9830
zhpan@med.wayne.edu
|
|
Visual information processing in the retina;
Gene therapy for treating blinding retinal degeneration. |
Molecular biology, electrophysiological recordings, immunocytochemistry, viral-based gene targeting, and animal behavior. |
|
| John Kamholz
313-577-0925
jkamholz@genetics.wayne.edu
|
 |
Myelin Sheath, Multiple Sclerosis, Charcot-Marie Tooth Disease. |
Knockout Mice |
|
| Gregory Kapatos
313-577-5965
gkapato@med.wayne.edu
|
 |
Cellular and molecular biology of monoamine neurotransmitter secreting neurons. |
Neurosciences |
|
| Donald Kuhn
313-577-9737
aa3071@wayne.edu
|
|
Molecular neurobiology of drug- and injury-induce damage to the brain |
All molecular, biochemical and cell biological approaches;
development of transgenic and knockout mice, fluorescence microscopy, HPLC |
|
| Jeffrey Loeb
313-577-9827
jloeb@med.wayne.edu
Lab Information |
 |
Developmental neuroscience;
molecular mechanisms in synapse formation;
neuregulins and neurotrophins in synaptic development;
functional genomic study of the pathogenesis of epilepsy and ALS. |
Developmental biology, electroporation Knockout, transgenic mouse models of human disease Biochemistry, Cell Biology, Drug development Human tissue studies, electrophysiology of epilepsy Functional genomics and systems biology |
|
| Naftali Raz
313-577-2297
nraz@wayne.edu
|
|
Brain aging, its impact on cognitive performance, and modification of aging by vascular risk factors |
MRI, cognitive tests |
|
| Robert Skoff
313-577-1165
rskoff@med.wayne.edu
|
 |
Disorders of brain white matter disease |
Tissue culture of neuroglial cells, molecular and cellular analyses of transgenic mice, electron microscopy |
|
| Derek Wildman
313-577-1253
dwildman@genetics.wayne.edu
Lab Information |
 |
Evolutionary genome analysis;
evolution of mammalian parturition. |
Whole genome sequencing;
pyrosequencing;
functional genomics, computation. |
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