Quick Look• Graduated from Wayne State University with a BS in Biotechnology in 2005
• Currently a sixth-year student in the PhD program
My appreciation of the training curriculum here at Wayne State stretches back to my undergraduate years. As an undergraduate student, I was exposed to the excellence in scientific study that is present here at the university. As a graduate student, I was particularly drawn to the emphasis that the program at the Center for Molecular Medicine and Genetics places on human genetics. The Center provides an excellent environment in which I can learn the skills necessary to contribute to the ever-expanding field of human genetics. I am most interested in pursuing study in human genetic disorders, specifically the genetics of abdominal aortic aneurysms (AAAs). Within the next three years, I hope to graduate and obtain a postdoctoral position.
My primary research interest is to study the evolution of encephalization in mammals. I propose to take two different approaches to study mammalian brain size. First, I would like to reconstruct the history of mammalian brain size evolution in a phylogenetic context to determine encephalization patterns among the different species. Second, I propose to take a comparative genomics approach to test for adaptive evolution of brain-expressed genes on lineages of encephalized species.
Sherwood CC, Raghanti MA, Stimpson CD, Spocter MA, Uddin M, Boddy AM, Wildman DE, Bonar CJ, Lewandowski AH, Philips KA, Erwin JM, Hof PR. Inhibitory interneurons of the human prefrontal cortex display conserved evolution of the phenotype and related genes. Proc. R. Soc. B, 2009.
Elmore JR, Obmann MA, Kuivaniemi H, Tromp G, Gerhard GS, Franklin DP, Boddy AM, Carey DJ. Identification of a genetic variant associated with abdominal aortic aneurysms on chromosome 3p12.3 by genome wide association. J Vasc Surg, 2009, 49(6):1525-1531.
Nischan J, Lenk GM, Boddy AM, Lillvis JH, Tromp G, Kuivaniemi H. Abdominal aortic aneurysms – a complex genetic disease. In: Aneurysms: Types, Risks, Formation and Treatment, Nova Science Publishers, Inc., Hauppauge, NY. E Morel E and Laurent A, eds. 2009: (in press).
Kuivaniemi H, Boddy AM, Lillvis JH, Nischan J, Lenk GM, Tromp G. Abdominal aortic aneurysms are deep, deadly and genetic. In: Aortic Aneurysms, New insights into an old problem. Liege University Press, Liege, Belgium. Sakalihasan N, Kuivaniemi H, and Michel JB, eds. 2008; 299-323.
Boddy AM, Lenk GM, Lillvis JH, Nischan J, Kyo Y, Kuivaniemi H. Basic research studies to understand aneurysm disease. Drug News and Perspectives, 2008, 21(3):142-148.