Quick Look• B.A. in Biological Sciences from SUNY at Buffalo in 2010
• Fourth year PhD student
I decided to join the CMMG program because of the amount and variety of world class research occurring in the department along with the collaborations between the clinic and other departments throughout Wayne State University. It also gives me an excellent opportunity to build upon research I was involved in as and undergrad and to further my knowledge and techniques as I move through rotations into a permanent lab. The CMMG has the faculty and resources that will allow me to perform any research in the future no matter what direction it will be in and CMMG will allows me to reach the greatest potential in that research.
• Advisor: Alexander Gow, PhD.
• My work in Dr. Gow's lab
involves characterization of a novel mouse model of
Multiple Sclerosis (MS), the most common
neurological disease affecting young adults in the
U.S. In contrast to current chemical induction
or artificial stimulation of the immune system used
in most models of MS, our model utilizes cell stress
from natural occurring mutation to trigger
disease. Through the use of in vivo imaging,
and ex vivo
imaging and analysis techniques we are looking to
determine the consequence of our cell stress in
causing neurodegeneration and phenotypes reminiscent
of those seen in patients, and determine to what
extent the immune system is activated. The
mouse model, and this study should provide novel
insight into the pathogenesis of MS and hopefully
lead to future treatments of therapies aimed at
preventing or mitigating the disease.