Opportunities to participate in research projects in Molecular
Medicine and Genetics are available as part of the Center for Molecular
Medicine and Genetics SURP. Areas of study include, cell cycle
regulation, chromosome structure and function, gene regulation,
molecular neurobiology, differentiation and development, molecular
biology of cancer, genetic engineering, genetics of cardiovascular
diseases, computational biology, and molecular evolution
Russell L. Finley, Jr.
Regulatory networks that control cell proliferation; cell cycle
regulation during development; yeast technology.
Molecular pathogenesis of CNS diseases; molecular characterization of
the claudin family of integral membrane tight junction proteins during
development in brain, testes and inner ear using transgenic and
homologous recombination in embryonic stem cells.
Lawrence I. Grossman,
Molecular genetics and evolution of the electron transport chain;
cytochrome c oxidase; mitochondria and mitochondrial diseases.
Henry H.Q. Heng, Molecular
cytogenetics; high order structure of chromosomes; genome structure and
function; genetic and physical mapping; genomic instability and cancer.
Hüttemann, Function of cytochrome c oxidase
isoforms, oxygen sensing, and role of mitochondria in cancer.
Cellular and molecular biology of monoamine neurotransmitter secreting
Stephen A. Krawetz,
Gene therapy; control of development and differentiation; expression of
connective tissue genes and genes controlling spermatogenesis;
computer-assisted sequence analysis.
Leonard Lipovich , The impact of primate-specific
genes on phenotypes, pathways, and human health; Genomics,
bioinformatics, long noncoding-RNA genes, and integrated functional
Li Li, Gene regulation during
cardiovascular and hematopoietic development.
Understanding the genetic and molecualr basis of inter-individual and
inter-population differences in complex phenotyps.
Developing comutational methods and statistical models to further our
understanding of the human genome
Michael Tainsky, Inherited
cancer and genomic instability; control of transcription in cancer
cells; Li-Fraumeni familial cancer syndrome.
Jeffrey Tseng, Protein
structure, function, classification and evolution; Disease-associated
non-synonymous single-nucleotide polymorphism; Geometric matching
techniques; Geometric modeling and
Kezhong Zhang, Signaling
pathways from the endoplasmic reticulum and mitochondria; unfolded
protein response, oxidative stress and inflammation in health and
Ren Zhang, Obesity and
diabetes; the leptin signaling pathway and mechanisms of leptin
resistance; comparative genomics.