Opportunities to participate in research projects
in Molecular Medicine and Genetics are available
as part of the Center for Molecular Medicine and
Genetics SURP. Areas of study include, cell cycle
regulation, chromosome structure and function,
gene regulation, molecular neurobiology,
differentiation and development, molecular biology
of cancer, genetic engineering, genetics of
cardiovascular diseases, computational biology,
and molecular evolution
Below are the research interests of CMMG faculty
participating in SURP:
L. Finley, Jr. Regulatory networks that
control cell proliferation; cell cycle
regulation during development; yeast technology.
Gow, Molecular pathogenesis of
CNS diseases; molecular characterization of the
claudin family of integral membrane tight
junction proteins during development in brain,
testes and inner ear using transgenic and
homologous recombination in embryonic stem
I. Grossman, Molecular genetics and
evolution of the electron transport chain;
cytochrome c oxidase; mitochondria and
H.Q. Heng, Molecular cytogenetics; high
order structure of chromosomes; genome structure
and function; genetic and physical mapping;
genomic instability and cancer.
Hüttemann, Function of cytochrome c
oxidase isoforms, oxygen sensing, and role of
mitochondria in cancer.
Kapatos, Cellular and molecular
biology of monoamine neurotransmitter secreting
A. Krawetz, Gene therapy;
control of development and differentiation;
expression of connective tissue genes and genes
controlling spermatogenesis; computer-assisted
Leonard Lipovich , The impact of
primate-specific genes on phenotypes, pathways,
and human health; Genomics, bioinformatics, long
noncoding-RNA genes, and integrated functional
Li, Gene regulation during cardiovascular
and hematopoietic development.
Luca, Understanding the genetic
and molecualr basis of inter-individual and
inter-population differences in complex
comutational methods and statistical models to
further our understanding of the human genome
Tainsky, Inherited cancer and genomic
instability; control of transcription in cancer
cells; Li-Fraumeni familial cancer syndrome.
Uddin, Investigating the molecular
underpinnings of commonly occurring mood-anxiety
disorders, with a particular emphasis on
post-traumatic stress disorder (PTSD).
Tseng, Protein structure, function,
classification and evolution;
Geometric matching techniques;
Geometric modeling and molecular simulation.
Zhang, Signaling pathways from the
endoplasmic reticulum and mitochondria; unfolded
protein response, oxidative stress and
inflammation in health and disease.
Zhang, Obesity and diabetes; the leptin
signaling pathway and mechanisms of leptin
resistance; comparative genomics.