Gerald Feldman, MD, PhD

Gerald Feldman, MD, PhD
Professor of Molecular Medicine and Genetics, Pathology and Pediatrics
Division Director for Clinical Genetics, CMMG
Director, Clinical Genetics Services
Medical Director, Division of Laboratory Genetics and Molecular Pathology, Detroit Medical Center-University Laboratories
Scott Hall, Rm 2375
540 E. Canfield Avenue
Detroit, MI 48201


PhD: Virginia Commonwealth University/Medical College of Virginia, 1982
MD:  Virginia Commonwealth University/Medical College of Virginia, 1984

Research Focus

Use of molecular technologies in the diagnosis of genetic diseases, clinical genetics, and dysmorphology; educational programs in medical genetics residency training, Newborn screening and inborn errors of metabolism

Recent Publications

Bannick AB, Laufman J, Edwards H, Ventimiglia J and Feldman, GL.  Outcomes of Referrals to Child Protective Services in Patients with Phenylketonuria: Experiences at a Single Treatment Center.  Molec Genet and Metab 2015 115(4):  151-156.  doi: 10. 1016/j.ymgme.2015.06.003.  Epub 2015  Jun 16.

Edwards JG, Feldman, GL, Goldberg J, Gregg AR, Norton ME, Rose NC, Schneider A, Stoll K, Wapner R and Watson MS.  Expanded Carrier Screening in Reproductive Medicine – Points to Consider. A joint statement of the American College of Medical Genetics and Genomics, American College of Obstetricians and Gynecologists, National Society of Genetic Counselors, Perinatal Quality Foundation and Society for Maternal Fetal Medicine.  Obstet Gynecol 2015:125-1-11.

Jay AM, Conway, RL, Feldman, GL, Nahhas F, Spencer L and Wolf, B.  Outcomes of individuals with profound and partial Biotinidase deficiency ascertained by newborn screening in Michigan over 25 years.  Genet Med epub advance publication 2014; doi:10.1038/gim.2014.104.

Li H, Spencer L, Nahhas F, Miller J, Fribley A, Feldman GL, Conway R and Wolf B.  Novel mutations causing Biotinidase deficiency in individuals identified by newborn screening in Michigan including a unique intronic mutation that alters mRNA expression of the Biotinidase gene.  Molecular Genetics and Metabolism 2014.  112:242-246.

Feldman GL, Schrijver I, Lyon E, Palomaki GE. Results of the College of American Pathology/American College of Medical Genetics and Genomics external proficiency testing from 2006 to 2013 for three conditions prevalent in the Ashkenazi Jewish population. Genet Med. 2014 Feb 27. doi: 10.1038/gim.2014.14. [Epub ahead of print] PubMed PMID: 24577267.

Richards CS, Palomaki GE, Lacbawan FL, Lyon E, Feldman GL; CAP/ACMG Biochemical and Molecular Genetics Resource Committee. Three-year experience of a CAP/ACMG methods-based external proficiency testing program for laboratories offering DNA sequencing for rare inherited disorders. Genet Med. 2014 Jan;16(1):25-32. doi: 10.1038/gim.2013.65. Epub 2013 May 23. PubMed PMID: 23703682.

Cichon M, Feldman GL. Opportunities to improve recruitment into medical genetics residency programs: survey results of program directors and medical genetics residents. Genet Med. 2013 Oct 17. doi: 10.1038/gim.2013.161. [Epub ahead of print] PubMed PMID: 24136619.

Nahhas FA, Monroe TJ, Prior TW, Botma PI, Fang J, Snyder PJ, Talbott SL, Feldman GL. Evaluation of the human fragile X mental retardation 1 polymerase chain reaction reagents to amplify the FMR1 gene: testing in a clinical diagnostic laboratory. Genet Test Mol Biomarkers. 2012 Mar;16(3):187-92. doi: 10.1089/gtmb.2011.0128. Epub 2011 Oct 12. PubMed PMID: 21992462.

Lacbawan FL, Weck KE, Kant JA, Feldman GL, Schrijver I; Biological and Molecular Genetic Resource Committee of the College of American Pathologists. Verification of performance specifications of a molecular test: cystic fibrosis carrier testing using the Luminex liquid bead array. Arch Pathol Lab Med. 2012 Jan;136(1):14-9. doi: 10.5858/arpa.2010-0536-OA. PubMed PMID: 22208482.