Stephen A. Krawetz, PhD

Stephen A. Krawetz, PhD
Professor of Obstetrics and Gynecology and of Molecular Medicine and Genetics
Charlotte B. Failing Professor of Fetal Therapy and Diagnosis
Associate Director, C.S. Mott Center for Human Grown and Development
C.S. Mott, Rm 253
275 E. Hancock
Detroit, MI 48201
313-577-6770
steve@compbio.med.wayne.edu

Education

University of Toronto, PhD, 1983

Research Focus

Gene Therapy; control of development and differentiation; expression of connective tissue genes and genes controlling spermatogenesis; computer-assisted sequence analysis.
Goal: To achieve a Systems Biology level understanding of the genetic mechanism(s) that controls the selection of genes for development and differentiation.

Recent Publications

Legro RS, Brzyski RG, Diamond MP, Coutifaris C, Schlaff WD, Alvero R, Casson P, Christman GM, Huang H, Yan Q, Haisenleder DJ, Barnhart KT, Bates GW, Usadi R, Lucidi R, Baker V, Trussell JC, Krawetz SA, Snyder P, Ohl D, Santoro N, Eisenberg E, Zhang H; National Institute of Child Health and Human Development Reproductive Medicine Network. The Pregnancy in Polycystic Ovary Syndrome II study: baseline characteristics and effects of obesity from a multicenter randomized clinical trial. Fertil Steril. 2014 Jan;101(1):258-269.e8. doi: 10.1016/j.fertnstert.2013.08.056. Epub 2013 Oct 21. PubMed PMID: 24156957; PubMed Central PMCID: PMC3899700.

Abdallah BY, Horne SD, Stevens JB, Liu G, Ying AY, Vanderhyden B, Krawetz SA, Gorelick R, Heng HH. Single cell heterogeneity: why unstable genomes are incompatible with average profiles. Cell Cycle. 2013 Dec 1;12(23):3640-9. doi: 10.4161/cc.26580. Epub 2013 Oct 1. PubMed PMID: 24091732; PubMed Central PMCID: PMC3903715.

Jodar M, Selvaraju S, Sendler E, Diamond MP, Krawetz SA; Reproductive Medicine Network. The presence, role and clinical use of spermatozoal RNAs. Hum Reprod Update. 2013 Nov-Dec;19(6):604-24. doi: 10.1093/humupd/dmt031. Epub 2013 Jul 14. PubMed PMID: 23856356; PubMed Central PMCID: PMC3796946.

Stevens JB, Liu G, Abdallah BY, Horne SD, Ye KJ, Bremer SW, Ye CJ, Krawetz SA, Heng HH. Unstable genomes elevate transcriptome dynamics. Int J Cancer. 2013 Oct 10. doi: 10.1002/ijc.28531. [Epub ahead of print] PubMed PMID: 24122714.