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Gerard Tromp

Original publications in refereed journals

  1. Sippola-Thiele, M., Tromp, G.C., Prockop, D.J. and Ramirez, F. Assessment of small polymorphisms in defined human collagen gene segments. Hum. Genet. 72:245-247, 1986.
  2. de Wet, W., Sippola, M., Tromp, G., Prockop, D., Chu, M.-L. and Ramirez, F. Use of R- loop mapping for the assessment of human collagen mutations. J. Biol. Chem. 261:3857-3862, 1986.
  3. Kuivaniemi, H., Tromp, G., Chu, M.-L. and Prockop, D.J. Structure of a full-length cDNA clone for the prepro-alpha2(I) chain of human type I procollagen. Comparison with the chicken gene confirms unusual patterns of gene conservation. Bioch. J. 252:633-640, 1988.
  4. Tromp, G. and Prockop, D.J. Single base mutation in the pro-alpha2(I) collagen gene that causes efficient splicing of RNA from exon 27 to exon 29 and synthesis of a shortened but in-frame pro-alpha2(I) chain. Proc. Natnl. Acad. Sci. U.S.A. 85:5254-5258, 1988.
  5. Kuivaniemi, H., Tromp, G., Chu, M.-L. and Prockop, D.J. Structure of a full-length cDNA clone for the prepro-alpha2(I) chain of human type I procollagen. Comparison with the chicken gene confirms unusual patterns of gene conservation. Biochem. J. 252:633- 640, 1988.
  6. Kuivaniemi, H., Sabol, C., Tromp, G., Sippola-Thiele, M. and Prockop, D.J. A 19-base pair deletion in the pro-alpha2(I) gene of type I procollagen that causes in-frame RNA splicing from exon 10 to exon 12 in a proband with atypical osteogenesis imperfecta and in his asymptomatic mother. J. Biol. Chem. 263:11407-11413, 1988.
  7. Tromp, G., Kuivaniemi, H., Stacey, A., Shikata, H., Baldwin, C.T., Jaenisch, R. and Prockop, D.J. Structure of a full-length cDNA clone for the prepro-alpha1(I) chain of human type I procollagen. Biochem. J. 253:919-911, 1988.
  8. Tromp, G., Kuivaniemi, H., Shikata, H. and Prockop, D. J. A single base mutation that substitutes serine for glycine 790 of the a1(III) chain of type III procollagen exposes an arginine and causes Ehlers-Danlos syndrome IV. J. Biol. Chem. 264:1349-1352, 1989.
  9. Tromp, G., Kuivaniemi, H., Stolle, C., Pope, F.M. and Prockop, D.J. Single base mutation in the type III procollagen gene that converts the codon for glycine 883 to aspartate in a mild variant of Ehlers-Danlos syndrome IV. J. Biol. Chem. 264:19313- 19317, 1989.
  10. Kontusaari, S., Tromp, G., Kuivaniemi, H., Ladda, R.L. and Prockop, D.J. Inheritance of an RNA splicing mutation (G+1 IVS20) in the type III procollagen gene (COL3A1) in a family having aortic aneurysms and easy bruisability: phenotypic overlap between familial arterial aneurysms and Ehlers-Danlos syndrome type IV. Am. J. Hum. Genet. 47:112-120, 1990.
  11. Kuivaniemi, H., Kontusaari, S., Tromp, G., Zhao, M., Sabol, C. and Prockop, D.J. Identical G+1 to A mutations in three different introns of the type III procollagen gene (COL3A1) produce different patterns of RNA splicing in three variants of Ehlers-Danlos syndrome IV. An explanation for exon skipping with some mutations and not others. J. Biol. Chem. 265:12067-12074, 1990.
  12. Kontusaari, S., Tromp, G., Kuivaniemi, H., Romanic, A. and Prockop, D.J. A mutation in the gene for type III procollagen (COL3A1) in a family with aortic aneurysms. J. Clin. Invest. 86:1465-1473, 1990.
  13. Zafarullah, K., Kleinert, C., Tromp, G., Kuivaniemi, H., Kontusaari, S., Wu, Y., Ganguly, A. and Prockop, D.J. G to A polymorphism in exon 31 of the human pro-alpha1(III) collagen gene. Nucleic Acids Res. 18:6180, 1990.
  14. Vasan, N.S., Kuivaniemi, H., Vogel, B.E., Minor, R.R., Wootton, J.A.M., Tromp, G., Weksberg, R. and Prockop, D.J. A mutation in the pro-alpha2(I) gene (COL1A2) for type I procollagen in Ehlers-Danlos syndrome type VIIB. Skipping of exon 6 in RNA splicing may be a common cause of the phenotype. Am. J. Hum. Genet. 48:305-317, 1991.
  15. Tromp, G., Kleinert, C., Kuivaniemi, H. and Prockop, D.J. C to T polymorphism in exon 33 of the COL3A1 gene. Nucl. Acids Res. 19:681, 1991.
  16. Sokolov, B.P., Prytkov, A.N., Tromp, G., Knowlton, R.G. and Prockop, D.J. Exclusion of COL1A1, COL1A2, and COL3A1 genes as candidate genes for Ehlers-Danlos syndrome type I in one large family. Human Genetics 88:125-129 (1991).
  17. Tromp, G., Christiano, A.M., Goldstein, N., Indik, Z., Rosenbloom, J., Boyd, C.D., Deak, S.B., Prockop, D.J. and Kuivaniemi, H. A to G polymorphism in exon 20 of the elastin gene. Nucleic Acids Res. 19:4314, 1991.
  18. Mays, P.K., Tromp, G., Kuivaniemi, H., Ryynänen, M. and Prockop, D.J. A 15 base- pair AT-rich variable number tandem repeat in the type III procollagen gene (COL3A1) as an informative marker for 2q31-2q32.3. Matrix 12: 44-49, 1992.
  19. Strobel, D., Tsuneyoshi, T., Kuivaniemi, H., Tromp, G., Spotila, L.D., Baldwin, C.T., Constantinou, C.D., Ganguly, A., Sereda, L., Sokolov, B. and Prockop, D.J. Three new polymorphisms at the COL1A2 locus. Matrix 12:87-91, 1992.
  20. Zhuang, J., Tromp, G., Kuivaniemi, H., Nakayasu, K. and Prockop, D.J. Deletion of 19 bp in intron 13 of the gene for pro-alpha2(I) chain of type I procollagen (COL1A2) causes exon skipping in a proband with type I osteogenesis imperfecta. Hum. Genet. 91:210- 216, 1993.
  21. Kontusaari, S., Tromp, G., Kuivaniemi, H., Stolle, C., Pope, F.M. and Prockop, D.J. Substitution of aspartate for glycine 1018 in type III procollagen (COL3A1) causes type IV Ehlers-Danlos syndrome. The mutated allele is present in most blood leukocytes of the asymptomatic and mosaic mother. Am. J. Hum. Genet. 51: 497-507, 1992.
  22. Narcisi, P., Wu, Y., Tromp, G., Earley, J.J., Richards, A.J., Pope, F.M. and Kuivaniemi, H. A single base mutation that substitutes glutamic acid for glycine 1021 in the COL3A1 gene and causes Ehlers-Danlos syndrome type IV. Am. J. Med. Genet. 46:278-283, 1993.
  23. Wu, Y., Kuivaniemi, H., Tromp, G., Strobel, D., Romanic, A.M. and Prockop, D.J. Temperature sensitivity of aberrant RNA splicing with a mutation in the G+5 position of intron 37 of the gene for type III procollagen from a patient with Ehlers-Danlos syndrome type IV. Hum. Mut. 2: 28-36, 1993.
  24. Tromp, G., Wu, Y., Prockop, D.J., Madhatheri, S.L., Kleinert, C., Earley, J.J., Zhuang, J., Norrgård, Ö., Darling, R.C., Abbott, W.M., Cole, C. W., , P., Ryynänen, M., Pearce, W.H., Yao, J.S.T., Majamaa, K., Smullens, S.N., Gatalica, Z., Ferrell, R.E., Jimenez, S.A., Jackson, C.E., Michels, V.V., Kaye, M. and Kuivaniemi, H. Sequencing of cDNA from 50 unrelated patients reveals that mutations in the triple-helical domain of type III procollagen are an infrequent cause of aortic aneurysms. J. Clin. Invest. 91:2539-2545, 1993.
  25. Kuivaniemi, H., Prockop, D.J., Wu, Y., Madhatheri, S.L., Kleinert, C., Earley, J. J., Jokinen, A., Stolle, C., Majamaa, K., Myllylä, V.V., Norrgård, Ö., Schievink, W.I., Mokri, B., Fukawa, O., ter Berg, H.W.M., De Paepe, A., Lozano, A. M., Leblanc, R., Ryynänen, M., Baxter, B.T., Shikata, H., Ferrell, R.E., and Tromp, G. Exclusion of mutations in the gene for type III collagen (COL3A1) as a common cause of intracranial aneurysms or cervical artery dissections: Results from sequence analysis of the coding sequences of type III collagen from 55 unrelated patients. Neurology 43:2652-2658, 1993.
  26. Earley, J.J., Kuivaniemi, H., Prockop, D.J. and Tromp, G. Efficient DNA sequencing on microtiter plates using dried reagents and Bst DNA polymerase. DNA Sequence 4:79- 85, 1993.
  27. Earley, J.J., Kuivaniemi, H., Prockop, D.J. and Tromp, G. Robotic automation of dideoxynucleotide sequencing reactions. BioTechniques 17: 156-165, 1994.
  28. Madhatheri, S.L. Tromp, G., Gustavson, K.-H. and Kuivaniemi, H. Substitution of glutamic acid for glycine 589 in the triple-helical domain of type III procollagen (COL3A1) in a family with variable phenotype of the Ehlers-Danlos syndrome type IV. Hum. Molec. Genet. 3:511-512, 1994.
  29. Tromp, G., De Paepe, A., Nuytinck, L., Madhatheri, S. and Kuivaniemi, H. Substitution of valine for glycine 793 in the triple-helical domain of type III procollagen in a mother and a child with the Ehlers-Danlos syndrome type IV. Hum. Mutat. 5:179-181,1995.
  30. Ronkainen, A., Hernesniemi, J. and Tromp, G. Special features of familial intracranial aneurysms: Report of 215 familial aneurysms. Neurosurgery 37:43-47, 1995.
  31. Thakker-Varia, S., Anderson, D.W., Kuivaniemi, H., Tromp, G., Shin, H.-G., van der Rest, M., Glorieux, F.H., Ala-Kokko, L. and Stolle, C.A. Aberrant splicing of the type III procollagen mRNA leads to intracellular degradation of the protein in a patient with Ehlers-Danlos type IV. Hum. Mutat. 6: 116-125, 1995.
  32. Zhuang, J., Tromp, G., Kuivaniemi, H., Castells, S. and Prockop, D.J. Substitution of arginine for glycine at position 154 of the a1 chain of type I collagen in a variant of osteogenesis imperfecta: comparison to previous cases with the same mutation. Am. J. Med. Genet. 61:111-116, 1996.
  33. Zhuang, J., Tromp, G., Kuivaniemi, H., Castells, S., Bugge, M. and Prockop, D.J. Direct sequencing of PCR products derived from cDNAs for the pro-alpha1 and pro-alpha2 chains of type I procollagen as a screening method to detect mutations in patients with osteogenesis imperfecta. Hum. Mut. 7: 89-99, 1996.
  34. Kuivaniemi, H. Tromp, G. Bergfeld, W.F., Kay, M. and Helm, T.N. Ehlers-Danlos syndrome type IV: A single base substitution of the last nucleotide of exon 34 in COL3A1 leads to exon skipping. J. Invest.Dermat. 105:352-356,1995.
  35. Hämäläinen, E.R., Kemppainen, R., Kuivaniemi, H., Tromp, G., Vaheri, A., Pihlajaniemi, T. and Kivirikko, K.I. Quantitative PCR of lysyl oxidase mRNA in malignantly transformed human cell lines demonstrates that their low lysyl oxidase activity is due to low quantities of its mRNA and low levels of transcription of the respective gene. J. Biol. Chem. 270:21590-21593,1995.
  36. Kemppainen, R., Hämäläinen , E.-R., Kuivaniemi, H., Tromp, G., Pihlajaniemi, T. and Kivirikko, K.I. Expression of mRNAs for lysyl oxidase and type III procollagen in cultured fibroblasts from patients with the Menkes and occipital horn syndromes as determined by quantitative polymerase chain reaction. Arch Bioch Biophys 328:101-106, 1996
  37. Jaakkola P, Kuivaniemi H, Partanen K, Tromp G, Liljestrom B and Ryynänen M. Familial abdominal aortic aneurysms: screening of 71 families of patients with abdominal aortic aneurysms. Eur J Surg 162:611-617,1996.
  38. Tromp G, Kuivaniemi H, Raphael S, Ala-Kokko L, Christiano A, Considine E, Dhulipala R, Hyland, J, Jokinen A, Kivirikko S, Korn R, Madhatheri S, McCarron S, Pulkkinen L, Punnett H, Shimoya K, Spotila L, Tate A and Williams CJ. Genetic linkage of familial granulomatous inflammatory arthritis, skin rash and uveitis to chromosome 16. Am J Hum Genet. 59:1097-1107,1996.
  39. Anderson DW, Thakker-Varia S, Tromp G, Kuivaniemi H and Stolle CA. A glycine (415) to serine substitution results in imparied secretion and decreased thermal stability of type III procollagen in a patient with Ehlers-Danlos syndrome type IV. Hum Mutat 9:62-63, 1997.
  40. Körkkö J, Kuivaniemi H, Päässilta P, Zhuang J, Tromp G, De Paepe A, Prockop DJ and Ala-Kokko L. Two recurrent nucleotide mutations in the COL1A1 gene in four patients with osteogenesis imperfecta. About one-fifth of reported mutations are recurrent. Hum Mutat. 9:148-156, 1997.
  41. Ronkainen A, Hernesniemi J, Puranen M, Niemitukia L, Vanninen R, Ryynänen M, Kuivaniemi H and Tromp G. Familial intracranial aneurysms: MR angiography screening of asymptomatic first-degree relatives reveals an intracranial aneurysm in 9% of screened subjects. The Lancet 349:380-384, 1997.
  42. Zafarullah, K., Brown, E. M., Kuivaniemi, H., Tromp, G., Sieron, A., Fertala, A. and Prockop, D. J. Synthesis and conformational properties of a recombinant C-propeptide of human type III procollagen. Matrix Biology 16:201-209, 1997.
  43. Zafarullah, K., Sieron, A., Fertala, A., Tromp, G., Kuivaniemi, H. and Prockop, D. J. A recombinant homotrimer of type I procollagen that lacks the central two D-periods. The thermal stability of the triple helix is decreased by 2 to 4°C. Matrix Biology 16:245-253, 1997.
  44. Devoto, M., Shimoya, K., Caminis, J., Ott, J., Tenenhouse, A., Whyte, M., Sereda, L., Hall, S., Williams, C. J., Tromp, G., Kuivaniemi, H., Ala-Kokko, L., Prockop, D. J. and Spotila, L. D. A first-stage autosomal genome screen for genes predisposing to low bone mineral density in extended pedigrees. Eur. J. Human Genet. Eur. J. Hum. Genet. 6: 151-157, 1998.
  45. Kuivaniemi, H., Marshall, A., Ganguly, A., Chu, M.-L. and Tromp, G. Detection of sequence variants by direct sequencing and conformation sensitive gel electrophoresis (CSGE): fibulin-2 exhibits high degree of variability but has no structural changes concordant with abdominal aortic aneurysms. Eur. J. Hum. Genet. 6:642-646, 1998.
  46. Wang, X., Tromp, G., Cole, C. W., Verloes, A., Sakalihasan, N. and Kuivaniemi, H. Analysis of coding sequences for tissue inhibitor of metalloproteinases 1 (TIMP1) and 2 (TIMP2) in patients with aneurysms. Matrix Biology 18:121-124.
  47. Papponen, H., Toppinen, T., Baumann, P., Myllylä, V., Leisti, J., Kuivaniemi, H., Tromp, G. and Myllylä, R. Founder mutations and the high prevalence of myotonia congenital in northern Finland. Neurology 53:297-302, 1999.
  48. Kosir, M. A., Wang, W., Zukowski, K. L., Tromp, G., and Barber, J. Degradation of basement membrane by prostate tumor heparanase. Surgical Research 81:42-47, 1999.
  49. Yoon, S., Tromp, G., Vongpunsawad, S., Ronkainen, A., Juvonen, T. and Kuivaniemi, H. Genetic analysis of MMP3, MMP9 and PAI-1 in Finnish patients with abdominal or intracranial aneurysms. Bioch Biophys Res Comm 265:563-568, 1999.
  50. Kosir, M. A., Quinn, C. C., Wang, W. and Tromp, G. Matrix glycosaminoglycans in the growth phase of fibroblasts: more of the story in wound healing. J Surg Res 92:45-52, 2000. PubMed
  51. Virgin, J. E., Bailey, J. B., Hasteh, F., Neville, J., Cole, A. and Tromp, G. Crossing over is rarely observed with mitotic intragenic recombination in Schizosaccharomyces pombe. Genetics 157:63-77, 2001.
  52. Asano, E., Kuivaniemi, H., Huq, A. H. M., Tromp, G., Behen, M., Rothermel, R., Herron, J., and Chugani, D. C. A study on novel polymorphisms in the upstream region of vasoactive intestinal peptide receptor type 2 gene in autism. J Child Neurol 16:357-363, 2001.
  53. Välkkilä, M., Melkoniemi, M., Kvist, L., Kuivaniemi, H., Tromp, G., Ala-Kokko, L. Genomic organization of the human COL3A1 and COL5A2 genes: COL5A2 has evolved differently than the other minor fibrillar collagen genes. Matrix Biol 20:357-366, 2001.
  54. Salkowski, A., Tromp, G., Greb, A., Womble, D., and Kuivaniemi, H. Web-site based recruitment for research studies on abdominal aortic and intracranial aneurysms. Genet Testing 5:307-310, 2001.PubMed
  55. Kuivaniemi, H., Yoon, S., Shibamura, H., Skunca, M., Vongpunsawad, S., and Tromp, G. Primer-extension preamplified DNA is a reliable template DNA for genotyping. Clin Chem 48:1601-1604, 2002.
  56. Yoon, S., Kuivaniemi, H., Gatalica, Z., Olson, J. M., Butticè, G., Ye, S., Norris, B. A., Malcom, G. T., Strong, J. P., and Tromp, G. MMP13 promoter polymorphism is associated with atherosclerosis in the abdominal aorta of young black males. Matrix Biol 21:487-498, 2002.
  57. Olson, J. M., Vongpunsawad, S., Kuivaniemi, H., Ronkainen, A., Hernesniemi, J., Ryynänen, M., Kim, L.-L., and Tromp, G. Search for intracranial aneurysm susceptibility gene(s) using Finnish families. BMC Med Genet 3:7, 2002.
  58. Wang, X., Kuivaniemi, H., Bonavita, G., Williams, C. J., and Tromp, G. High-resolution physical map for chromosome 16q12.1-q13, the Blau syndrome locus. BMC Genomics 3:24, 2002.
  59. Wang, X., Kuivaniemi, H., Bonavita, G., Mutkus, L., Mau, U., Blau, E., Inohara, N., Nunez, G., Tromp, G., and Williams, C. J. NOD2/CARD15 mutations in familial granulomatosis syndromes: a study of the original Blau syndrome kindred and other families with large vessel arteritis and cranial neuropathy. Arthritis Rheum 46:3041-3045, 2002.
  60. Kuivaniemi, H., Shibamura, H., Arthur, C., Berguer, R., Cole, C. W., Juvonen, T., Kline, R. A., Limet, R., MacKean, G., Norrgård, Ö., Pals, G., Powell, J. T., Rainio, P., Sakalihasan, N., van Vlijmen-van Keulen, C., Verloes, A., and Tromp, G. Familial abdominal aortic aneurysms: Collection of 233 multiplex families. J Vasc Surg 37:340-345, 2003.
  61. Wills, S., Ronkainen, A., van der Voet, M., Kuivaniemi, H., Helin, K., Leinonen, E., Frösen, J., Niemelä, M., Jääskeläinen, J., Hernesniemi, J., and Tromp, G. Familial intracranial aneurysms: An analysis of 346 multiplex Finnish families. Stroke 34:1370-1374, 2003.
  62. Zhong, J., Zhang, H., Stanyon, C.A., Tromp, G., and Finley, R.L., Jr. A strategy for constructing large protein interaction maps using the yeast two-hybrid system: regulated expression arrays and two-phase mating. Genome Research 13:2691-2699, 2003
  63. Goddard, K.A., Olson, J.M., Payami, H., Van Der Voet, M., Kuivaniemi, H.and Tromp, G. Evidence of linkage and association on chromosome 20 for late-onset Alzheimer disease. Neurogenetics 5:121-128, 2004.
  64. Kim, Y.M., Romero, R., Chaiworapongsa, T., Kim, G.J., Kim, M.R., Kuivaniemi, H., Tromp, G., Espinoza, J., Bujold, E., Abrahams, V.M.and Mor, G. Toll-like receptor-2 and -4 in the chorioamniotic membranes in spontaneous labor at term and in preterm parturition that are associated with chorioamnionitis. Am J Obstet Gynecol 191:1346-1355, 2004.
  65. Shibamura, H., Olson, J.M., van Vlijmen-Van Keulen, C., Buxbaum, S.G., Dudek, D.M., Tromp, G., Ogata, T., Skunca, M., Sakalihasan, N., Pals, G., Limet, R., MacKean, G.L., Defawe, O., Verloes, A., Arthur, C., Lossing, A.G., Burnett, M., Sueda, T.and Kuivaniemi, H. Genome scan for familial abdominal aortic aneurysm using sex and family history as covariates suggests genetic heterogeneity and identifies linkage to chromosome 19q13. Circulation 109:2103-2108, 2004.
  66. Tanabe, T., Chamaillard, M., Ogura, Y., Zhu, L., Qiu, S., Masumoto, J., Ghosh, P., Moran, A., Predergast, M.M., Tromp, G., Williams, C.J., Inohara, N.and Nunez, G. Regulatory regions and critical residues of NOD2 involved in muramyl dipeptide recognition. Embo J 23:1587-1597, 2004.
  67. Theendakara, V., Tromp, G., Kuivaniemi, H., White, P.S., Panchal, S., Cox, J., Winters, R.S., Riebeling, P., Tost, F., Hoeltzenbein, M., Tervo, T.M., Henn, W., Denniger, E., Krause, M., Koksal, M., Kargi, S., Ugurbas, S.H., Latvala, T., Shearman, A.M.and Weiss, J.S. Fine mapping of the Schnyder's crystalline corneal dystrophy locus. Hum Genet 114:594-600, 2004.
  68. Tromp, G., Gatalica, Z., Skunca, M., Berguer, R., Siegel, T., Kline, R.A.and Kuivaniemi, H. Elevated Expression of Matrix Metalloproteinase-13 in Abdominal Aortic Aneurysms. Ann Vasc Surg 2004.
  69. Tromp, G., Kuivaniemi, H., Romero, R., Chaiworapongsa, T., Kim, Y.M., Kim, M.R., Maymon, E.and Edwin, S. Genome-wide expression profiling of fetal membranes reveals a deficient expression of proteinase inhibitor 3 in premature rupture of membranes. Am J Obstet Gynecol 191:1331-1338, 2004.
  70. van der Voet, M., Olson, J.M., Kuivaniemi, H., Dudek, D.M., Skunca, M., Ronkainen, A., Niemelä, M., Jääskeläinen, J., Hernesniemi, J., Helin, K., Leinonen, E., Biswas, M.and Tromp, G. Intracranial aneurysms in Finnish families: confirmation of linkage and refinement of the interval to chromosome 19q13.3. Am J Hum Genet 74:564-571, 2004.
  71. Wang, H., Parry, S., Macones, G., Sammel, M.D., Ferrand, P.E., Kuivaniemi, H., Tromp, G., Halder, I., Shriver, M.D., Romero, R.and Strauss, J.F., 3rd. Functionally significant SNP MMP8 promoter haplotypes and preterm premature rupture of membranes (PPROM). Hum Mol Genet 13:2659-2669, 2004.
  72. Gatalica, Z., Velagaleti, G., Kuivaniemi, H., Tromp, G., Palazzo, J., Graves, K.M., Guigneaux, M., Wood, T., Sinha, M.and Luxon, B. Gene expression profile of an adenomyoepithelioma of the breast with a reciprocal translocation involving chromosomes 8 and 16. Cancer Genet Cytogenet 156:14-22, 2005.
  73. Kim, G.J., Romero, R., Kuivaniemi, H., Tromp, G., Haddad, R., Kim, Y.M., Kim, M.R., Nien, J.K., Hong, J.S., Espinoza, J., Santolaya, J., Yoon, B.H., Mazor, M.and Kim, C.J. Expression of bone morphogenetic protein 2 in normal spontaneous labor at term, preterm labor, and preterm premature rupture of membranes. Am J Obstet Gynecol 193:1137-1143, 2005.
  74. Ogata, T., MacKean, G.L., Cole, C.W., Arthur, C., Andreou, P., Tromp, G.and Kuivaniemi, H. The lifetime prevalence of abdominal aortic aneurysms among siblings of aneurysm patients is eightfold higher than among siblings of spouses: an analysis of 187 aneurysm families in Nova Scotia, Canada. J Vasc Surg 42:891-897, 2005.
  75. Ogata, T., Shibamura, H., Tromp, G., Sinha, M., Goddard, K.A., Sakalihasan, N., Limet, R., MacKean, G.L., Arthur, C., Sueda, T., Land, S.and Kuivaniemi, H. Genetic analysis of polymorphisms in biologically relevant candidate genes in patients with abdominal aortic aneurysms. J Vasc Surg 41:1036-1042, 2005.
  76. Chatterjee, M., Mohapatra, S., Ionan, A., Bawa, G., Ali-Fehmi, R., Wang, X., Nowak, J., Ye, B., Nahhas, F.A., Lu, K., Witkin, S.S., Fishman, D., Munkarah, A., Morris, R., Levin, N.K., Shirley, N.N., Tromp, G., Abrams, J., Draghici, S.and Tainsky, M.A. Diagnostic markers of ovarian cancer by high-throughput antigen cloning and detection on arrays. Cancer Res 66:1181-1190, 2006.
  77. Haddad, R., Gould, B.R., Romero, R., Tromp, G., Farookhi, R., Edwin, S.S., Kim, M.R.and Zingg, H.H. Uterine transcriptomes of bacteria-induced and ovariectomy-induced preterm labor in mice are characterized by differential expression of arachidonate metabolism genes. Am J Obstet Gynecol 195:822-828, 2006.
  78. Haddad, R., Tromp, G., Kuivaniemi, H., Chaiworapongsa, T., Kim, Y.M., Mazor, M.and Romero, R. Human spontaneous labor without histologic chorioamnionitis is characterized by an acute inflammation gene expression signature. Am J Obstet Gynecol 195:394 e391-324, 2006.
  79. Hassan, S.S., Romero, R., Haddad, R., Hendler, I., Khalek, N., Tromp, G., Diamond, M.P., Sorokin, Y.and Malone, J., Jr. The transcriptome of the uterine cervix before and after spontaneous term parturition. Am J Obstet Gynecol 195:778-786, 2006.
  80. Meftah, S.P., Kuivaniemi, H., Tromp, G., Kerkeni, A., Sfar, M.T., Ayadi, A.and Prasad, A.S. A new mutation in exon 3 of the SCL39A4 gene in a Tunisian family with severe acrodermatitis enteropathica. Nutrition 2006.
  81. Ogata, T., Arrington, S., Davis, P.M., Jr., Sam, A.D., 2nd, Hollier, L.H., Tromp, G. and Kuivaniemi, H. Community-Based, Nonprofit Organization-Sponsored Ultrasonography Screening Program for Abdominal Aortic Aneurysms Is Effective at Identifying Occult Aneurysms. Ann Vasc Surg 2006.
  82. Ogata, T., Gregoire, L., Goddard, K.A., Skunca, M., Tromp, G., Lancaster, W.D., Parrado, A.R., Lu, Q., Shibamura, H., Sakalihasan, N., Limet, R., Mackean, G.L., Arthur, C., Sueda, T.and Kuivaniemi, H. Evidence for association between the HLA-DQA locus and abdominal aortic aneurysms in the Belgian population: a case control study. BMC Med Genet 7:67, 2006.
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