Basic Neuroscience Publications:

Loeb JA and Fischbach GD (1997) Neurotrophic factors increase neuregulin expression in embryonic ventral spinal cord neurons.  J.  Neurosci.  17:1416-1424.

Loeb JA, Susanto, E and Fischbach GD (1998). The neuregulin precursor proARIA is processed to ARIA after expression on the cell surface by a protein kinase C-enhanced mechanism.  Mol. Cell. Neurosci.  11:77-91.

Loeb JA, Khurana TS, Robbins J, Yee AG, and Fischbach GD. (1999) Expression Patterns of Transmembrane and Released forms of Neuregulin During Spinal Cord and Neuromuscular Synapse Development.  Development 126:781-791.

Ford BD, Loeb JA, and Fischbach GD. (1999) Neuregulin stimulates DNA synthesis in embryonic chick heart cells. Dev. Biol. 214:139-150.

Li Q, Loeb JA (2001) Neuregulin-HSPG interactions produce sustained ErbB receptor activation required for the induction of AChRs in muscle. J Biol. Chem. 276:38068-38075.

Loeb JA, Hmadcha A, Fischbach GD, Land SJ, and Zakarian VL (2002) Neuregulin Expression at Neuromuscular Synapses is Modulated by Synaptic Activity and Neurotrophic Factors, J.  Neurosci. 22:2206-2214.

Loeb JA (2003) Neuregulin: An Activity-Dependent Synaptic Modulator at the Neuromuscular Junction. J Neurocytol. 32:649-664.

Li Q, Esper RM, and Loeb JA (2004) Synergistic Effects of Neuregulin and Agrin on Muscle Acetylcholine Receptor Expression. Mol. Cell. Neurosci. 26:558-69.

Esper RM and Loeb JA (2004) Rapid axoglial signaling mediated by neuregulin and neurotrophic factors.  J. Neurosci. 24:6218-27.

Yao B, Rakhade SN, Li Q, Ahmed A, Krauss R, Draghici S, and Loeb JA (2004) Accuracy of cDNA microarray methods to detect small gene expression changes induced by neuregulin on breast epithelial cells BMC Bioinformatics 2004, 5:99

Li Q, Ahmed S, and Loeb JA (2004) Development of a proliferative autocrine neuregulin signaling loop during the malignant transformation of human breast epithelial cells. Cancer Research 64:7078-85

Pankonin MS, Gallagher JT, Loeb JA. (2005) Specific structural features of heparan sulfate proteoglycans potentiate neuregulin-1 signaling.. J Biol Chem. 280(1):383-8.

Taveggia C, Zanazzi G, Petrylak A, Yano H, Rosenbluth J, Einheber S, Xu X, Esper RM, Loeb JA, Shrager P, Chao MV, Falls DL, Role L, Salzer JL. (2005) Neuregulin-1 type III determines the ensheathment fate of axons. . Neuron. 47(5):681-94.

Rakhade SN, Yao B, Ahmed S, Asano E, Beaumont TL, Shah AK, Draghici S, Krauss R, Chugani HT, Sood S, Loeb JA.. (2005) A common pattern of persistent gene activation in human neocortical epileptic foci. Ann Neurol. 58(5):736-47.

Hapner SJ, Nielsen KM, Chaverra M, Esper RM, Loeb JA, Lefcort F (2006) NT-3 and CNTF exert pleiotropic effects in the immature dorsal root ganglion including neuregulin-mediated proliferation of progenitor cells and neuronal differentiation. Dev. Biol. 297(1):182-97.

Esper RM, Pankonin, MS, Loeb JA (2006) Neuregulins: Versatile growth and differentiation factors in nervous system development and human disease, Brain Res. Rev. , 51:161-75.

Loeb JA (2007) Neuroprotection and repair by neurotrophic and gliotrophic factors in multiple sclerosis, Neurology 68;38-42..

Rakhade SN, Shah AK, Agarwal R, Yao B, Asano E, Loeb JA (2007) Activity-Dependent Gene Expression Correlates with Interictal Spiking in Human Neocortical Epilepsy.  Epilepsia, (in press).

Rakhade SN and Loeb JA (2007) Regional Down-regulation of Neuronal Glutamate Transporters at Human Neocortical Epileptic Foci, Epilepsia, (in press)..

Clinical Neuroscience Publications:

Loeb JA (1998) Functional improvement in a patient with basal ganglia calcification using a bisphosphonate.  Movement disorders 13:345-349.

Loeb JA (1998) Features of Leao's spreading depression in patients with lesions near sensory cortex. J. Epilepsy 11:110-115.

Loeb JA (2002) Recertification for neurologists, (Post publication peer review; letter to the editor) Neurology (on-line).

Li J, Loeb JA, Shy ME, Shah AK, Tselis AC, Kupski WJ, and Lewis RA (2003) Asymmetric flaccid paralysis: A neuromuscular presentation of West Nile virus infection.  Ann. Neurol. 53:703-10.

Nash TE, Del Brutto OH, Butman JA, Corona T, Delgado-Escueta A, duron R, Evans CAW, Gilman RH, Gonzalez AE, Loeb JA, Medina MT, Pietch-Escueta S, Pretell EJ, Takayanagui OM, Theodore W, Tsang VCW, Garcia HH (2004) Calcific neurocysticercosis and epileptogenesis. Neurology  62: 1934-38.

Maslinksi PG an d Loeb JA (2004) Pica-Associated Cerebral Edema in an Adult. J Neurol. Sci 225:149-151. 

Loeb JA, Sohrab SA, Huq M, Fuerst, D (2006) Brain calcifications induce neurological dysfunction that can be reversed by a bone drug J. Neurol. Sci. 243:77-81.

TE. Nash, G Singh, AC White, V Rajshekhar, JA Loeb, JV  Proaño, OM Takayanagui, AE Gonzalez, JA Butman, C DeGiorgio, OH. Del Brutto, A Delgado-Escueta, CAW Evans, RH Gilman, SM Martinez, MT Medina,  J Pretell,  J Teale, HH. Garcia (2006) Treatment of Neurocysticercosis - Current Status and Future Research Needs. Neurology, 67(7):1120-7.

 Shah AK, Agarwal R, Carhupoma JR, Loeb JA (2006) Compressed EEG pattern analysis for critically ill neurological-neurosurgical patients.  Neurocritical Care 5(2):124-33.