Tiffany Cook, PhD

Lawrence I. Grossman, PhD

Associate Professor of Molecular Medicine and Genetics and of Ophthalmology
Scott Hall, Rm 3206
540 E. Canfield Avenue
Detroit, MI 48201
313-577-9461
Email

Education and Training:

Mayo Graduate School, Rochester MN, PhD, 1997

Research Focus

Molecular basis of eye development and disease; differentiation and maintenance of neuronal and non-neuronal cell types in the Drosophila retina; glial support mechanisms; cell-specific transcriptional regulatory mechanisms; cell-cell interactions involved in sensory system development and function.

Selected Publications

Stahl AL, Baucom RS, Cook TA, Buschbeck EK.  A complex lens for a complex eye.  Integr Comp Biol. 2017 Sep; icx116. 

Charlton-Perkins MA, Sendler ED, Buschbeck EK, Cook TAMultifunctional glial support by Semper cells in the Drosophila retina. PLoS Genet. 2017 May ;13(5):e1006782.

Friedrich M, Cook T, Zelhof AC.  Default activators of terminal photoreceptor differentiation in the pancrustacean compound eye: the homeodomain transcription factors Otd and Pph13. Curr Opin Insect Sci 2016 Feb; 13:33-42

Luebbering N, Charlton-Perkins M, Kumar JP, Lochead PA, Rollmann SM, Cook T, Cleghon V. Drosophila Dyrk2 plays a role in the development of the visual system. PLoS One. 2013 Oct 11;8(10):e76775.

Jukam D, Xie B, Rister J, Terrell D, Charlton-Perkins M, Pistillo D, Gebelein B, Desplan C, and Cook T. Opposite network-level feedback in the Hippo pathway for growth regulation and post-mitotic neural fate. Science 2013; 342(6155):1238016. 

Riazuddin S, Belyantseva IA, Giese AP, Lee K, Indzhykulian AA, Nandamuri SP, Yousaf R, Sinha GP, Lee S, Terrell D, Hegde RS, Ali RA, Anwar S, Andrade-Elizondo PB, Sirmaci A, Parise LV, Basit S, Wali A, Ayub M, Ansar M, Ahmad W, Khan SN, Akram J, Tekin M, Riazuddin S, Cook T, Buschbeck EK, Frolenkov GI, Leal SM, Friedman TB, Ahmed ZM. Alterations of the CIB2 calcium- and integrin-binding protein cause Usher syndrome type 1J and nonsyndromic deafness DFNB48. Nat Genet. 2012 Nov;44(11):1265-71.

Terrell D, Xie B, Workman M, Mahato S, Zelhof A, Gebelein B, Cook T. OTX2 and CRX rescue overlapping and photoreceptor-specific functions in the Drosophila eye. Dev Dyn. 2012 Jan;241(1):215-28.

Charlton-Perkins M, Brown NL, Cook TA. The lens in focus: a comparison of lens development in Drosophila and vertebrates. Mol Genet Genomics. 2011 Oct;286(3-4):189-213.

Charlton-Perkins M, Whitaker SL, Fei Y, Xie B, Li-Kroeger D, Gebelein B, Cook T. Prospero and Pax2 combinatorially control neural cell fate decisions by modulating Ras- and Notch-dependent signaling. Neural Dev. 2011 May 3;6:20.

 

View "My Bibliography" from NCBI